First ladies and gentlemen of Bolivia

First Lady of Bolivia
Incumbent Lourdes Brigida Durán Romero since 8 November 2020
Residence	Palacio Quemado, La Paz
Inaugural holder	Manuela Sáenz
Formation	12 August 1825

The First Lady or First Gentleman of Bolivia (Spanish: Primera Dama o Primer Caballero de Bolivia) is the title usually attributed to the wife or husband of the president of Bolivia, or official designee in place of a spouse. She or he fulfills official protocol functions when accompanying the president.

The position of First Lady of Bolivia is currently held by Lourdes Brigida Durán Romero, wife of President Luis Arce, since he assumed the presidency on 8 November 2020.